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Short courses & CPD
Biosciences

Introduction to downstream bioprocessing

This 3-day course explores conventional downstream bioprocessing methods and operations used in modern biomanufacturing facilities.

 

3 days

 
  • Note: For a limited time, enjoy a 50% discount on this programme as part of our partnership with the RESILIENCE Centre of Excellence for UK Medicines Manufacturing Skills.
 

Course overview

This course is designed for scientists, manufacturing operators, and process engineers new to downstream processing and industrial chromatography. You will review the basics of biomolecule purification and expand your knowledge on design, optimisation, and troubleshooting of downstream processes.

5 Reasons why you should study this course:

  • Fundamentals: gain a solid understanding of downstream processing fundamentals, including chromatography and purification techniques.
  • Quality attributes: learn about critical quality attributes and common quality testing techniques in downstream processing.
  • Viral control: explore viral inactivation and clearance, along with flocculation, essential for pharmaceutical manufacturing.
  • Filtration techniques: get introduced to normal and crossflow filtration operations, understanding their advantages and constraints.
  • Practical skills: delve into protein capture, purification, and polishing methods, enhancing your practical expertise in downstream processing.

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Course details

What you study

Downstream processing overview and fundamentals
Critical quality attributes in the context of downstream operations
Viral clearance and flocculation
Flow filtration techniques (normal and tangential)
Chromatography systems
Protein capture and purification
Polishing methods

How you learn

Delegates will be given the opportunity to apply their theoretical knowledge of bioprocessing procedures through a series of practical sessions using the Cytiva AKTA platform and associated Unicorn software. Training will be conducted in our Centre of Excellence facility housing cutting-edge laboratory instruments and benchtop-scale processing equipment, allowing delegates to gain vital hands-on practical exposure to industry-standard biomanufacturing processes and procedures.

How you are assessed

No assessment required.

 

Entry requirements

Entry requirements

Scientists, manufacturing operators and process engineers new to downstream processing and industrial chromatography who want to review the basics of biomolecule purification. Individuals who are interested in expanding their knowledge on design, optimisation and troubleshooting of downstream processes.

 

Employability

Career opportunities

Downstream Process Development Scientist
Protein Purification Specialist
Biomanufacturing Technician
Quality Control Analyst
Process Engineer

 
 

Part-time

2024/25 entry

Fee for applicants:
£2,250

+ VAT

  • Length: 3 days
  • Start date: TBC

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